Hydrophilic AIOL with bonding

ABSTRACT

An accommodating intraocular lens comprises a first lens component, a second lens component, and an adhesive between portions of the two lens components. The cured adhesive bonds the lens components to form a fluid chamber. The lens components are bonded to one another along a seam which extends circumferentially along at least a portion of the lens components. The lens components may comprise the same polymer material. The cured adhesive also comprises the polymer or a prepolymer of the polymer to provide increased strength. The polymer is hydratable such that the lens components and the cured adhesive therebetween can swell together to inhibit stresses between the lens components and the cured adhesive.

CROSS-REFERENCE TO RELATED APPLICATION(S)

This application is a continuation of U.S. patent application Ser. No.14/181,145, entitled “HYDROPHILIC AIOL WITH BONDING,” filed Feb. 14,2014, now U.S. Pat. No. 9,486,311, which claims the benefit of U.S.Provisional Application No. 61/764,699, entitled “HYDROPHILIC AIOL,”filed Feb. 14, 2013, and U.S. Provisional Application No. 61/764,715,entitled “HYDROPHILIC AIOL,” filed Feb. 14, 2013, the contents of whichare incorporated herein by reference in their entireties.

BACKGROUND

The eye is critical for vision. As people age, the crystalline lens ofthe eye may move less than ideally, a condition referred to aspresbyopia. For presbyopes with good distance vision, reading glassesmay be required for near vision. Although multifocal lenses can behelpful, such lenses can provide more than one focal point of the eyeand provide less than ideal vision. As the eye ages further, thecrystalline lens may have cataracts that degrade vision, requiringremoval of the crystalline lens and replacement with an intraocularlens. Although intraocular lenses can be helpful to restore vision, suchlenses may not restore accommodation and in many instances provide afixed focal length of the eye.

Although accommodating intra ocular lenses (hereinafter “AIOLs” or“accommodating IOL”) have been proposed, the prior AIOLs can provideless than ideal results in at least some instances. At least some of theprior AIOLs provide less than ideal amounts of accommodation. Also, asthe amount of force of the capsular bag can be somewhat less than ideal,at least some of the prior IOLs may provide less than ideal amounts ofaccommodation in response to the forces of the capsular bag. Further,work in relation to embodiments suggests that the prior AIOLs may beless than ideally suited for insertion into the eye in at least someinstances. Clinically, an incision that is larger than ideal may resultin astigmatism of the eye, and it would be helpful if an accommodatingIOL could be inserted through small incision. Also, the prior AIOLs canbe somewhat more difficult to manufacture than would be ideal. AIOLs tocorrect vision can be machined to very accurate tolerances, and softmaterials can be more difficult to machine than would be ideal in atleast some instances. Also, work in relation to embodiments suggeststhat prior methods and apparatus of bonding AIOLs can be less thanideal.

For the above reasons, improved AIOLs, and methods of manufacture anduse are needed.

SUMMARY

Embodiments of the present disclosure provide improved accommodating IOLmethods and apparatus. In many embodiments, an accommodating IOLcomprises a first lens component and a second lens component eachcomposed of a polymer, and adhesive comprising the polymer. In manyembodiments, the polymer can be hydrated and swells with hydration, suchthat the first component, the second component, and the adhesive swelltogether (e.g., at the same or substantially similar rate). By swellingtogether, stresses among the first component, the second component, andthe adhesive can be inhibited substantially. Also, the hydratableadhesive allows the first and second components to be machined in astiff less than fully hydrated configuration prior to adhering of thecomponents together. The stiff configuration may comprise a less thanfully hydrated polymer, such as a substantially dry polymer. Thecomponents can be bonded together in the stiff substantiallyconfiguration to facilitate handling during manufacturing, andsubsequently hydrated such that the components bonded the adhesivecomprise a soft hydrated configuration for insertion into the eye. Theadhesive comprising the polymer can bond the first and second lenscomponents together with chemical bonds similar to the polymer materialitself in order to provide increased strength.

The first component comprises a first disk shaped structure and thesecond component comprises a second disc shaped structure. An annularstructure extends between the first disc shaped structure and the seconddisc shaped structure to define a chamber containing a fluid having anindex of refraction greater than about 1.336, which is the index ofrefraction of the aqueous humor of the eye. When one or more of thefirst disk structure or the second disk structure increases incurvature, optical power of the IOL increases. The adhesive can bond thefirst component to the second component by extending circumferentiallyaround one or more of the annular structure, the first disc shapedcomponent, the second disc shaped component, and combinations thereof.In many embodiments, the adhesive is located in a seam extendingcircumferentially around the one or more of the annular structure, thefirst disc shaped component, the second disc shaped component, andcombinations thereof, which bonds the components together. Locating theseam away from the optical portions of the first and second componentsprovides improved optical properties. Also, the adhesive comprising thepolymer of the first and second components swells similarly to the firstand second components, and can be particularly helpful when providedcircumferentially around the first and second component, as thesecomponents can swell substantially along the diameter. Decreasingstresses along bonds of an accommodating IOL can be particularly helpfulas the IOL can be made smaller to decrease insertion size and maycomprise thin deformable structures configured to deform with decreasedstresses.

In many embodiments, the first and second components are machined on alathe to provide rotationally symmetric structures, such as the firstdisc shaped structure and the second disc shaped structure. One or moreof the first component or the second component may comprise the annularstructure prior to bonding the components together. One or more annulargrooves can be provided on the first component and the second componentin order to align optically the first component with the secondcomponent. The adhesive can be placed in the groove and cured when thefirst component and the second component comprise the stiffsubstantially dry configuration.

In many embodiments, the adhesive comprises a prepolymer of the polymerof the components. The prepolymer may comprise one or more of a monomer,an oligomer, a partially cured monomer, particles, or nano particles ofthe polymer.

The accommodating IOL may comprise one or more haptics to couple thedisc shaped components to the capsular bag in order to change theoptical power of the lens in response to deformations of the capsularbag. In many embodiments, the one or more haptics comprise chambersfluidically coupled to the chamber comprising the first and second lenscomponents. The haptics can be made of a soft material such as asilicone, for example.

All publications, patents, and patent applications mentioned in thisspecification are herein incorporated by reference to the same extent asif each individual publication, patent, or patent application wasspecifically and individually indicated to be incorporated by reference.

BRIEF DESCRIPTION OF THE DRAWINGS

The novel features of the disclosure are set forth with particularity inthe appended claims. A better understanding of the features andadvantages of the present disclosure will be obtained by reference tothe following detailed description that sets forth illustrativeembodiments, in which the principles of the disclosure are utilized, andthe accompanying drawings of which:

FIG. 1 illustrates a perspective view of an accommodating intra ocularlens system, in accordance with many embodiments;

FIG. 2 illustrates a side view of a lens support structure and lens, inaccordance with many embodiments;

FIG. 3 illustrates a sectioned view of a lens support structureincorporating a lens interfaced using threads, in accordance with manyembodiments;

FIG. 4 illustrates a sectioned view of a lens support structureincorporating a lens interfaced using an interference fit, in accordancewith embodiments;

FIG. 5 illustrates a perspective view of an alternative accommodatingintra ocular lens system, in accordance with many embodiments;

FIG. 6 illustrates a sectioned view of an alternative accommodatingintra ocular lens system, in accordance with many embodiments;

FIG. 7 illustrates a sectioned view of an alternative accommodatingintra ocular lens system, in accordance with many embodiments;

FIG. 8 illustrates a sectioned view of an alternative accommodatingintra ocular lens system, in accordance with many embodiments;

FIG. 9 shows a perspective view of a support structure for the AIOL ofFIG. 8, in accordance with alternate embodiments of the AIOL of FIG. 8;

FIG. 10 shows a method of manufacturing an AIOL, in accordance with manyembodiments; and

FIG. 11 shows an optical structure deformed to provide optical power.

DETAILED DESCRIPTION

In many embodiments, an accommodating intra ocular lens system (AIOL)comprises a central structure comprising two deformable lenses spacedapart along their optical axis by an outer support structure concentricwith the optical axis of the lenses. The volume bounded by the lensesand the outer support structure may be filled with a fluid, such as anionic solution (saline). Alternatively or in combination, other fluidscan be used such as oil, silicone oil, or solutions comprising highmolecular weight molecules such as high molecular weight dextransolution, for example. In such solutions of high molecular weightmaterials, the solute may increase the refractive index while the highmolecular weight of the solute may inhibit the diffusion of the solutefrom the inner chamber. The outer support structure in turn may bebounded by one or more fluid filled haptics arranged in a plane normalto the optical axis of the lenses. The haptics may be in fluidcommunication with the fluid bounded by the inner support structure. Thetransfer of fluid between the haptics and the fluid filled supportstructure may change the accommodating power of the lens system. Thesystem as described herein may additionally comprise any or anycombination of the following features:

A reduced delivery cross section is facilitated by an internal supportstructure capable of translating from a delivery configuration to anoperational configuration. The inner support structure may have a smalldimension along the optical axis in the delivery configuration andlarger dimension along the optical axis in operational configuration.The inner support structure may be designed to maintain the distancebetween the periphery of the two lenses in the operational configurationand to allow fluid to pass between the haptics and the volume bounded bythe internal support structure.

The delivery cross section can be attained by folding or rolling theAIOL around a delivery axis normal to the optical axis. The deliverycross section may be measured as the largest dimension in the deliveryconfiguration measured in a plane normal to the delivery axis. Deliverycross sections attainable for the AIOLS described herein may be lessthan 4.5 mm, and preferably less than 2.5 mm.

The lens system may comprise of at least two hydrophilic PMMA lenses,and may include other elements comprising any or any combination of thefollowing materials: NiTi, poly urethane, hydrophilic PMMA, photoactivated polymers, precursors to PMMA, poly(hydroxy ethyl) methacrylate(PHEMA), copolymers of polymethyl methacrylate and PHEMA, and Ethyleneglycol dimethylacrylate.

In some embodiments, the internal support structure comprises a materialwhich is changed from a delivery configuration to an operationconfiguration after introduction into the capsule of the eye. One suchmaterial comprises a photo active polymer which in the deliveryconfiguration may be a liquid which can be hardened by photo activationafter introduction. Another such material comprises a memory metal suchas an NiTi alloy which in the delivery configuration may have a thindimension in a plane normal to the optical axis and after introductionmay be initiated to change to an operational configuration by heatingvia inductive coupling or body heat, alternatively or in combination.

The internal support structure in some embodiments is mechanically morestable in the operational configuration than in the deliveryconfiguration, and spontaneously changes from a delivery configurationto an operational configuration after introduction into the capsule ofthe eye. In such a configuration the internal support structure may becoaxed into a delivery configuration just prior to delivery or atmanufacture.

One such system comprises a super elastic metal element which springsfrom the delivery configuration upon introduction of the device into thecapsule.

In some embodiments, the inner support structure and one lens aremachined or molded as a single structure and the second lens is affixedto the support structure by an alternate means. Alternate means includemechanical interfaces such as threading where the outer periphery of thelens is threaded and the inner surface of the support structure isthreaded. In an alternate embodiment, the interface can be a simpleinterference fit. In some embodiments, affixing comprises bonding thematerials by treating the one or both of the separate bonding surfaceswith a precursor monomer, then assembling the structure, applying a loadacross the bonding surfaces, and heating the assembly for a period oftime.

In the devices of the present disclosure, the lenses may comprise awater and ion permeable material. In some embodiments, the AIOL isallowed to self fill after implantation, thereby minimizing the deliverycross section.

In an alternate embodiment, the AIOL is filled after implant.

The lenses and some of the support structures described herein arefabricated from a hydrophilic material such as a copolymer ofhydroxyethyl methacrylate and methyl methacrylate such as CI18, CI21, orCI26 produced by Contamac Ltd. of the UK. These materials are opticallyclear when hydrated, swell on hydration by more than 10% (for example,by 10-15%), and accommodate strain levels of greater than 100% whenhydrated. When fully hydrated, these materials may have a water contentof 15 to 30%. For example, CI18 when fully hydrated may be composed of18% water, CI21 when fully hydrated may be composed of 21% water, andCI26 when fully hydrated may be composed of 26% water. In asubstantially dry state or configuration, these materials may be have awater content of no more than about 5%, for example 0.2-3%. Thesematerials are often oven dried prior to machining

FIG. 1 illustrates an accommodating intraocular lens system 10 which maycomprise a central lens support structure 11, two haptics 12, twodeformable lenses 13 of which only one is visible in the figure, and twocompression bands 14. The haptics may comprise thin walled structuresconfigured to deform under minimal loads and comprise an elastomericmaterial. The internal volume of the AIOL can be filled with a clearfluid such as saline of comparable osmolality to that of the fluids inthe eye around the lens capsule. The lenses 13 may be interfaced to thesupport structure 11 such that as fluid transfers from the haptics intothe internal volume of the support structure the lenses are caused todeform thereby changing their accommodative power. A side view of thelens support structure 11 of FIG. 1 along with two lenses 13 isillustrated in FIG. 2. Also visible in FIG. 2 are the haptic interfacefeatures 15 comprised in the lens support structure 11. The open end ofthe haptics 12 may fit over the haptic interface features 15 and may befurther affixed to the lens support structure interface feature 15 usingcompression bands 14. Additionally, in some embodiments, an adhesive orsealant may be used. The distance between the periphery of the lens canbe maintained by the support structure while the centre of the lens maybe allowed to deform as the fluid volume within the support structureincreases, thereby changing the accommodative power of the structure.

FIG. 3 illustrates a lens support structure in which one of the twolenses, lens 36 is comprised in the support structure. The second lensin the embodiment of FIG. 3 may be designed to interface to the supportstructure via threads 37. Another embodiment for a central supportstructure similar to that of FIG. 3 is illustrated in FIG. 4. In thisembodiment, the second lens 43 may be interfaced via an interferencefit. In some embodiment, the interference fit may be further sealedthrough the use of a sealant or adhesive. The interference fit may befurther facilitated by the procedure used to assemble and rehydrate thecomponents. One such procedure as implemented on the structure of FIG. 4may be as follows: the bottom of the support structure 41 comprisinglens 46 may be hydrated, the lens 43 in the unhydrated condition canthen be fitted into the groove comprised in the support structure 41,the support structure and lenses may be allowed to completely hydrate,and, if required, a sealant or adhesive may then be applied. The use ofinterference fits can minimize the requirement and or amount of bondingagent.

FIG. 5 illustrates another embodiment of an AIOL 50 in which half of thesupport structure 41 and haptics 42 may be comprised in an upper andlower half of the AIOL 50 and thereby all fabricated from the samematerial. The two halves may be bonded together at seam 59 to form thecomplete haptic and support structure. Lens 53 may either be integral tothe half structures as or bonded to the support structure. In themanufacturing environment allowing one lens to be aligned and bondedafter the fabrication of the rest of the structure provides advantage inassuring the optical axis of the two lenses are precisely aligned.

In the embodiments of FIGS. 1 and 2, the haptics are configured in sucha fashion that they may be folded out and away from the supportstructure in a plane normal to the optical axis of the lenses. Such aconfiguration may facilitate a reduction in delivery cross section for afluid filled device. In the embodiment of FIG. 6 through 7, the hapticsmay be both integral to the support structure and attached continuouslyaround the perimeter of the support structure.

FIG. 6 illustrates an embodiment of an AIOL 60 wherein the haptic 62 andthe support structure 61 are integral and are configured as a toroidlike structure. The inner radius of the structure comprises the supportstructure 61. Fluid may be allowed to flow between the haptic 62 and theinner volume of the support structure 61 through openings 67. The AIOL60 can be fabricated by bonding the two halve at seam 59. Lens 63 may beintegral with the halves are bonded separately to the halves.

A variation on the embodiment of FIG. 6 is illustrated in FIG. 7. Theembodiment of the AIOL 70 may incorporate features which help to reducethe delivery cross section. Half of the support structure may becomprised on each the upper and lower halves on the AIOL 70 andcomprises a series of structures 71 each separated by as space forming acastellated ring. Castellated structures can be meshed at assembly priorto bonding at seam 79. Spring ring 79 may fit in a grove and may lockthe upper and lower halves of the structure relative to displacementsalong the optical axis. As shown in FIG. 7, the lenses 73 can beintegral to the half structures comprising the AIOL 70. In otherembodiments, the lenses 73 may be separate and bonded at another time.In such an embodiment, the support structure is capable of greaterdeformation during delivery as the castellated elements can fold over agreater radius of curvature. AIOL 70 also comprises feature 78, whichallows for a means of applying pressure directly across seam 79 duringthe bonding process.

FIG. 8 represents an embodiment of an AIOL 80 which comprises anelastomeric support structure 81 filled with a fluid capable of beinghardened after delivery of the AIOL. Such fluids may be optically cured,such as a UV curing silicone or epoxy, pH cured such as a collagensolution, or heat cured where the material contains a suspension ofparticle capable of being inductively heated such as magnititeparticles. Channels 87 may allow fluid to pass between the haptic andthe central volume of the support structure.

FIG. 9 shows a support structure 81 in accordance with an alternateembodiment of AIOL 80. The support structure 81 may be replaced with asupport structure 91 which comprises a memory metal which can beflattened prior to assemble then headed by inductive coupling allow itto take an operation configuration after delivery, such a configurationprovides for a reduced cross section.

Embodiments described herein also allow for sequencing the assembly andthe use of long setting, heat, pressure, and or optical initiatedbonding materials to insure proper optical alignment of the lenses.

Bonding

Bonding can be used to bond one or more of many AIOL structures asdisclosed herein.

Bonding of a copolymer of hydroxyethyl methacrylate and methylmethacrylate may be facilitated by treating the bond surfaces with anEthylene glycol dimethylacrylate or Ethylene glycol trimethylacrylate.Then, the bonded surfaces may be subjected to pressure and temperature.Treatment may include but is not limited to vapor treatment, wetting,wetting and allowing for evaporation, applying a mixture of Ethyleneglycol dimethylacrylate or Ethylene glycol trimethylacrylate andparticles of a copolymer of hydroxyethyl methacrylate and methylmethacrylate.

Such a bonding scheme can provide advantage in that there is no orminimal seam—the bonded interface has the same mechanical properties asthe structure.

Each of the components can be provided in a stiff configuration formachining and bonded together with the adhesive while in a stiffconfiguration. The component can be subsequently hydrated.

The prepolymer of the adhesive may comprise one or more of Ethyleneglycol dimethylacrylate or Ethylene glycol trimethylacrylate, and theprepolymer can be cured to bond the first and second componentstogether. The precursor monomers may be partially or fully polymerizedby the addition of an initiator. The initiator may be a photoinitiatorsuch as Irgacure 651 (I651, Ciba-Geigy), or an initiator such as2,2′-azobis(isobutyonitrile), 2,2′-azobis(2,4-dimethylvaleronitrile),dilauroyl peroxide and bis(4-t-butylcyclohexyl)peroxydicarbonate, forexample.

In many embodiments, the first and second lens components comprise acopolymer of hydroxyethyl methacrylate and methyl methacrylate. Whencured, the adhesive comprises the copolymer of hydroxyethyl methacrylateand methyl methacrylate. This configuration can allow the lens to expandfrom a stiff less than fully hydrated configuration, to the fullyhydrated configuration with substantially swelling and inhibited stressto the components and the adhesive located along the seam. The stiff,less than fully hydrated configuration of the polymer material will beunderstood by a person of ordinary skill in the art to comprise apolymer having a sufficiently low amount of water to provide stiffnessto the polymer material of the first and second components. The lessthan fully hydrated configuration may comprise a substantially dryconfiguration composed of no more than about 5% water, for example0.2-3% water, such that the polymer material comprises sufficientstiffness for machining the material to optical tolerances as will bereadily understood by a person of ordinary skill in the art. When theAIOL is placed in the lens capsule or placed in a hydration buffer asunderstood by a person of ordinary skill in the art, for example, thepolymer may swell to a hydrated state and gradually to a fully hydratedstate. The polymer in the fully hydrated state may be composed of about15% to 30% water, for example, depending on the material selected. Thepolymer in the fully hydrated state may swell by more than 10%, such as10% to 15%.

FIG. 10 shows a method 1000 of manufacturing and providing an AIOL.

At a step 1010, a block of polymer material as described herein isprovided. The block of material is cut into a first component 1012 and asecond component 1014. The polymer material comprises a stiffconfiguration as described herein.

At a step 1020, the first component 1012 and the second component 1014are shaped into first lens component 1022 and second lens component 1024of the AIOL. The components can be shaped in one or more of many wayssuch as turning on a lathe, cutting, ablation, and other known methodsof shaping optical lenses. Alternatively or in combination, thecomponents may be molded. One or more of the components 1022, 1024comprises a feature 1026 shaped to receive the opposing component (thefeature 1026 may comprise an annular groove, for example). A channel1028 can be provided to allow fluidic communication with the chamber1036 of the AIOL. Alternatively or in combination, the channel 1028 canbe formed when the first and second components are bonded together.

At a step 1030, the first and second components 1022, 1024 are bondedtogether with an adhesive 1032 provided in the feature 1026. The firstcomponent 1022 and the second component 1024 define a chamber 1036.

The adhesive 1032 comprises a prepolymer of the polymer of thecomponents 1012 and 1014. Although the components are shown providedfrom a single block, the polymer material can be provided with separateblocks of material having similar polymer composition.

A haptic 1038 can be affixed to the AIOL 1035, such that an internalchamber of the IOL is fluidically coupled to the chamber of the haptic.The haptic may comprise a material similar to the AIOL, or a differentmaterial. The haptic 1038 may have a thickness 1039. For example, theAIOL may comprise an acrylate as described herein and the haptic 1038may comprise a soft silicon material. The haptic may comprise a softmaterial inserted into the AIOL when the AIOL comprises a stiffconfiguration, for example.

The AIOL in the stiff configuration comprises a dimension 1034 across,such as a diameter. The AIOL may comprise a thickness 1048 extendingbetween an anterior most portion of the AIOL body and the posterior mostportion of the AIOL body.

At a step 1040, the AIOL 1035 is hydrated to a substantially hydratedconfiguration to decrease stiffness, such that the AIOL comprises a softmaterial. In the hydrated configuration dimensions of the AIOL increase,and may increase proportionally to each other. In many embodiments, theincrease comprises a similar percentage increase along each dimension.

In many embodiments, the amount of hydration in the stiff configurationcomprises a predetermined amount of hydration in order to accuratelymachine the lens components to an appropriate amount of refractive powerwhen the AIOL comprises the fully hydrated state when implanted in theeye.

The disc shaped optical structure of the upper component 1022 can beflat, or lens shaped, for example. The disc shaped optical structure ofthe lower component 1022 can be flat, or lens shaped, for example, suchthat one or more of the optical structures deforms to provide opticalpower.

FIG. 11 shows one or more of the optical structure deformed to provideoptical power with a curved surface 1100. The fluid of the AIOL can begreater than the index of refraction of 1.33 of the aqueous humor inorder to provide the increased optical power with curved surface 1100.

While reference is made to acrylates, the polymer and prepolymer maycomprise silicone hydrogel materials, for example.

While preferred embodiments of the present disclosure have been shownand described herein, it will be obvious to those skilled in the artthat such embodiments are provided by way of example only. Numerousvariations, changes, and substitutions will now occur to those skilledin the art without departing from the disclosure. It should beunderstood that various alternatives to the embodiments of thedisclosure described herein may be employed in practicing the inventionsof the disclosure. It is intended that the following claims define thescope of invention and that methods and structures within the scope ofthese claims and their equivalents be covered thereby.

We claim:
 1. A method of manufacturing an accommodating intraocularlens, the method comprising: providing a first lens component comprisinga first optical portion having a central optical axis, a first hapticportion surrounding the first optical portion, a first inner matingportion between the first optical portion and the first haptic portion,and a first annular outer mating portion positioned radially outwardfrom the first inner mating portion with respect to the central opticalaxis; providing a second lens component comprising a second opticalportion having a central optical axis coincident with the centraloptical axis of the first optical portion, a second haptic portionsurrounding the second optical portion, a second inner mating portionbetween the second optical portion and the second haptic portion, and asecond annular outer mating portion positioned radially outward from thesecond inner mating portion with respect to the central optical axis;and bonding the first inner mating portion of the first lens componentto the second inner mating portion of the second lens component at aninner seam and bonding the first annular outer mating portion with thesecond annular outer mating portion at an outer seam; wherein areservoir between the inner seam and the outer seam defines a hapticreservoir, a reservoir between the first optical portion and the secondoptical portion defines a lens chamber in fluid communication with thehaptic reservoir; and a distance between the first optical portion andthe second optical portion, as measured along the central optical axisof the first optical portion, is configured to change in response tomovement of fluid between the haptic reservoir and the lens chamber. 2.The method of manufacturing of claim 1, further comprising forming anopening in a portion of the first lens component, wherein the hapticreservoir is in fluid communication with the lens chamber via theopening.
 3. The method of manufacturing of claim 1, wherein bonding thefirst inner mating portion of the first lens component to the secondinner mating portion of the second lens component at an inner seamfurther comprises forming one or more openings between the first innermating portion and the second inner mating portion, and wherein thehaptic reservoir is in fluid communication with the lens chamber via theone or more openings.
 4. The method of manufacturing of claim 1, whereinthe first inner mating portion and the second inner mating portion eachcomprise a series of structures separated by spaces forming acastellated ring, and wherein the spaces form openings between the lenschamber and the haptic reservoir when the first inner mating portion isbonded to the second inner mating portion.
 5. The method ofmanufacturing of claim 1, wherein the haptic reservoir has a toroidalshape.
 6. The method of manufacturing of claim 1, further comprisingfilling the lens chamber and haptic reservoir with fluid.
 7. The methodof manufacturing of claim 6, wherein both the lens chamber and thehaptic reservoir are filled with the same fluid.
 8. The method ofmanufacturing of claim 6, wherein the fluid is one of an ionic solution,an oil, silicone oil, or high molecular weight dextran.
 9. The method ofmanufacturing of claim 6, wherein the fluid has an index of refractiongreater than 1.33.
 10. The method of manufacturing of claim 1, whereinthe first optical portion comprises a same material as one or more ofthe first haptic portion, the second optical portion, and the secondhaptic portion.
 11. The method of manufacturing of claim 1, furthercomprising hydrating the first lens component and the second lenscomponent after bonding the first lens component to the second lenscomponent.
 12. The method of manufacturing of claim 1, furthercomprising cutting a first component and a second component from one ormore blocks of material.
 13. The method of manufacturing of claim 12,further comprising shaping the first lens component from the firstcomponent and shaping the second lens component from the secondcomponent.
 14. The method of manufacturing of claim 1, wherein thebonding at the inner seam and at the outer seam is performed using anadhesive.
 15. The method of manufacturing of claim 14, wherein bondedinterfaces between the first lens component and the second lenscomponent have the same mechanical properties as the first and thesecond lens components.
 16. The method of manufacturing of claim 1,wherein the first haptic portion is attached to the first opticalportion continuously around a perimeter of the first optical portion.17. The method of manufacturing of claim 16, wherein the second hapticportion is attached to the second optical portion continuously around aperimeter of the second optical portion.